![Heterozygous missense mutations of ALPK1 in the cohort and overview of... | Download Scientific Diagram Heterozygous missense mutations of ALPK1 in the cohort and overview of... | Download Scientific Diagram](https://www.researchgate.net/publication/362205043/figure/fig1/AS:11431281086309678@1664206580885/Heterozygous-missense-mutations-of-ALPK1-in-the-cohort-and-overview-of-clinical.png)
Heterozygous missense mutations of ALPK1 in the cohort and overview of... | Download Scientific Diagram
Science News Highlights - Mechanism of gastric inflammation by Helicobacter pylori Helicobacter pylori's ADP-heptose binds to the kinase ALPK1 in gastric epithelial cells and directs activation of classical and alternative NF-κB pathways
![Frontiers | Alpk1 Sensitizes Pancreatic Beta Cells to Cytokine-Induced Apoptosis via Upregulating TNF-α Signaling Pathway Frontiers | Alpk1 Sensitizes Pancreatic Beta Cells to Cytokine-Induced Apoptosis via Upregulating TNF-α Signaling Pathway](https://www.frontiersin.org/files/Articles/705751/fimmu-12-705751-HTML-r1/image_m/fimmu-12-705751-g001.jpg)
Frontiers | Alpk1 Sensitizes Pancreatic Beta Cells to Cytokine-Induced Apoptosis via Upregulating TNF-α Signaling Pathway
![Role of NOD1 and ALPK1/TIFA Signalling in Innate Immunity Against Helicobacter pylori Infection | SpringerLink Role of NOD1 and ALPK1/TIFA Signalling in Innate Immunity Against Helicobacter pylori Infection | SpringerLink](https://media.springernature.com/lw685/springer-static/image/chp%3A10.1007%2F978-3-030-15138-6_7/MediaObjects/465513_1_En_7_Fig1_HTML.png)
Role of NOD1 and ALPK1/TIFA Signalling in Innate Immunity Against Helicobacter pylori Infection | SpringerLink
![ALPK1 and TIFA dependent innate immune response triggered by the Helicobacter pylori type IV secretion system | bioRxiv ALPK1 and TIFA dependent innate immune response triggered by the Helicobacter pylori type IV secretion system | bioRxiv](https://www.biorxiv.org/content/biorxiv/early/2017/05/19/139998/F7.large.jpg)
ALPK1 and TIFA dependent innate immune response triggered by the Helicobacter pylori type IV secretion system | bioRxiv
![ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder | Genetics in Medicine ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder | Genetics in Medicine](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41436-019-0476-3/MediaObjects/41436_2019_476_Fig1_HTML.png)
ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder | Genetics in Medicine
![Coordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC | bioRxiv Coordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC | bioRxiv](https://www.biorxiv.org/content/biorxiv/early/2022/07/20/2022.07.19.500647/F9.large.jpg)
Coordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC | bioRxiv
![Cancers | Free Full-Text | Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases Cancers | Free Full-Text | Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases](https://pub.mdpi-res.com/cancers/cancers-14-04390/article_deploy/html/images/cancers-14-04390-g003.png?1662728349)
Cancers | Free Full-Text | Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases
![ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder | Genetics in Medicine ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder | Genetics in Medicine](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41436-019-0476-3/MediaObjects/41436_2019_476_Fig3_HTML.png)
ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder | Genetics in Medicine
![Cancers | Free Full-Text | Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases Cancers | Free Full-Text | Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases](https://pub.mdpi-res.com/cancers/cancers-14-04390/article_deploy/html/images/cancers-14-04390-ag.png?1663037562)
Cancers | Free Full-Text | Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases
![In vitro kinase assay reveals ADP-heptose-dependent ALPK1 autophosphorylation and altered kinase activity of disease-associated ALPK1 mutants | Scientific Reports In vitro kinase assay reveals ADP-heptose-dependent ALPK1 autophosphorylation and altered kinase activity of disease-associated ALPK1 mutants | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-023-33459-7/MediaObjects/41598_2023_33459_Fig1_HTML.png)
In vitro kinase assay reveals ADP-heptose-dependent ALPK1 autophosphorylation and altered kinase activity of disease-associated ALPK1 mutants | Scientific Reports
ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria | PLOS Pathogens
![Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis | Nature Communications Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis | Nature Communications](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41467-018-06085-5/MediaObjects/41467_2018_6085_Fig7_HTML.png)